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Because the peptide is bio-identical, systemic side effects are rare

Nanocarriers can surmount these limitations by chemically conjugating or encapsulating the protein or peptide

New findings and a reevaluation of a major affirmative study

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Only an estimated 1%2% of oral B12 can be passively absorbed and therefore, high dosages of oral B12 are required to provide therapeutic benefit in cases where the receptor-mediated process malfunctions ( FIGURE 1 In the receptor-mediated absorptive process, ingested B12 is initially bound to Haptocorrin (HC)/R-factor secreted by salivary glands